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Puma Biotechnology vs Tango Therapeutics: PBYI and TNGX compared

Puma Biotechnology is the larger company: $55.1M of revenue in its latest quarter (Q3 2026) against $53.8M for Tango Therapeutics (Q3 2025). Tango Therapeutics is growing faster (+364% against +1% a year earlier). Tango Therapeutics is more profitable, with an operating margin of 26.2% against 9.6%.

Puma Biotechnology vs Tango Therapeutics, latest quarterPuma Biotechnology vs Tango Therapeutics, latest quarterPuma Biotechnology (PBYI)Tango Therapeutics (TNGX)Revenue$55.1M$53.8MRevenue growth, Y/Y+1%+364%Operating margin9.6%26.2%Net margin10.9%29.5%

Where the money goes: PBYI and TNGX

Puma Biotechnology (PBYI) · Q3 2026

Puma Biotechnology, Q3 2026: revenue $55.1M (+1% year over year), operating margin 9.6%, net earnings $6.0M. The chart follows the revenue to costs, profit and cash.

Tango Therapeutics (TNGX) · Q3 2025

Tango Therapeutics, Q3 2025: revenue $53.8M (+364% year over year), operating margin 26.2%, net earnings $15.9M, operating cash flow −$31.0M. The chart follows the revenue to costs, profit and cash.

Puma Biotechnology revenue by segment, Q3 2026Puma Biotechnology revenue by segment, Q3 2026Product revenue, net$54.1MRoyalty revenue$1.0M
Puma Biotechnology (PBYI)Tango Therapeutics (TNGX)
Latest quarterQ3 2026Q3 2025
Revenue$55.1M$53.8M
Revenue growth, Y/Y+1%+364%
Operating margin9.6%26.2%
Net earnings$6.0M$15.9M
Net margin10.9%29.5%
Operating cash flow—−$31.0M

Where the revenue comes from

Puma Biotechnology

Questions

Which is bigger, Puma Biotechnology or Tango Therapeutics?

Puma Biotechnology is the larger company: $55.1M of revenue in its latest quarter (Q3 2026) against $53.8M for Tango Therapeutics (Q3 2025).

Is Puma Biotechnology or Tango Therapeutics growing faster?

Tango Therapeutics is growing faster (+364% against +1% a year earlier).

Which is more profitable, Puma Biotechnology or Tango Therapeutics?

Tango Therapeutics is more profitable, with an operating margin of 26.2% against 9.6%.

More: Puma Biotechnology earnings · how Puma Biotechnology makes money · Tango Therapeutics earnings · how Tango Therapeutics makes money

From the companies' latest 10-Q, 10-K or earnings release (8-K filed Nov 5, 2026; 10-Q filed Nov 4, 2025). Fiscal quarters can end on different dates. Not investment advice.