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Puma Biotechnology (PBYI) earnings and revenue breakdown

Latest: Q3 2026 · 8-K filed Nov 5, 2026

Q3 2026 Revenue up 1% year over year to $55.1M · 11¢ of every $1 of revenue kept as net profit · operating margin 9.6%

Puma Biotechnology made $55.1M in Q3 2026 (+1% Y/Y): Product revenue, net $54.1M, Royalty revenue $1.0M. Operating margin 9.6%, net earnings $6.0M. See where every dollar goes — costs, profit and cash — as a Sankey from the 8-K filed Nov 5, 2026 (preliminary, from the earnings release).

Revenue$55.1M
Year over year+1%
Operating margin9.6%
Net earnings$6.0M
Operating cash flow—

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $55.1M in Q3 2026, up 1% year over year and down 2% from the previous quarter. Product revenue, net was the largest line at 98% of revenue. Product revenue, net added $2.2M year over year (up 4%), 352% of the total change. Royalty revenue declined 62%.

Operating profit was $5.3M, a 9.6% margin (down 8.0 points year over year). Operating profit fell $4.3M even though revenue rose $625K versus Q3 2025, so costs grew faster than sales. Total costs grew 11% against revenue growth of 1%. The fastest-growing cost line was Cost of revenue (+25%). Net earnings were $6.0M, down 32% year over year. The effective tax rate was 3.2%.

Quarterly history

Puma Biotechnology revenue by quarterPuma Biotechnology revenue by quarter$46.0MQ1 2025$52.4MQ2 2025$54.5MQ3 2025$75.5MQ4 2025$44.8MQ1 2026$56.5MQ2 2026$55.1MQ3 2026
Puma Biotechnology net earnings by quarterPuma Biotechnology net earnings by quarter$3.0MQ1 2025$5.9MQ2 2025$8.8MQ3 2025$13.4MQ4 2025−$3.8MQ1 2026$8.2MQ2 2026$6.0MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 20268-KNov 5, 2026$55.1M+1%9.6%$6.0M—
Q2 202610-QAug 6, 2026$56.5M+8%13.4%$8.2M$1.6M
Q1 202610-QMay 7, 2026$44.8M-3%-8.5%−$3.8M$15.4M
Q4 202510-KFeb 26, 2026$75.5M+28%22.7%$13.4M$14.4M
Q3 202510-QNov 6, 2025$54.5M-32%17.6%$8.8M$9.7M
Q2 202510-QAug 7, 2025$52.4M+11%12.7%$5.9M$14.1M
Q1 202510-QMay 8, 2025$46.0M+5%8.7%$3.0M$3.6M

Charts

Puma Biotechnology: revenue growth, year over year and quarter over quarterPuma Biotechnology: revenue growth, year over year and quarter over quarterY/YQ/Q+5%Q1 2025+11%+14%Q2 2025-32%+4%Q3 2025+28%+39%Q4 2025-3%-41%Q1 2026+8%+26%Q2 2026+1%-2%Q3 2026
Latest (Q3 2026): Y/Y +1%, Q/Q -2%.
Puma Biotechnology: where the cash came from (+) and went (−), TTM to Q2 2026Puma Biotechnology: where the cash came from (+) and went (−), TTM to Q2 2026Net borrowing (+) / repaid (−)−$44.5MOperating cash flow$41.1MCash drawn (+) / kept (−)$20.2MOther investing−$16.0MOther financing−$889KCapital spending$10K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Puma Biotechnology: profit against cash, quarter by quarterPuma Biotechnology: profit against cash, quarter by quarterNet incomeOperating cash flow$20.3M$11.0MQ3 2024$19.3M$15.6MQ4 2024$3.0M$3.6MQ1 2025$5.9M$14.1MQ2 2025$8.8M$9.7MQ3 2025$13.4M$14.4MQ4 2025−$3.8M$15.4MQ1 2026$8.2M$1.6MQ2 2026
Latest (Q2 2026): Net income $8.2M, Operating cash flow $1.6M.
Puma Biotechnology: diluted shares by fiscal yearPuma Biotechnology: diluted shares by fiscal year40MFY202041MFY202145MFY202248MFY202349MFY202451MFY2025
+28.0% since FY2020: more shares outstanding (issuance, stock pay).
Puma Biotechnology in its industry: growth against margin (225 companies, SIC 2834)Puma Biotechnology in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOTNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMPBYI (+1%, 10%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Puma Biotechnology

Puma Biotechnology, Inc. is a biopharmaceutical company with a focus on the development and commercialization of innovative products to enhance cancer care. Puma in-licensed the global development and commercialization rights to PB272 (neratinib, oral) in 2011. Neratinib, oral was approved by the U.S. Food and Drug Administration in 2017 for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer, following adjuvant trastuzumab-based therapy, and is marketed in the United States as NERLYNX® (neratinib) tablets. In February 2020, NERLYNX was also approved by the FDA in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting.

In its own words, from its 8-K, filed Aug 6, 2026.

Puma Biotechnology against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +1% against the peers' median +7%. Operating margin: 9.6% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
PBYI Puma BiotechnologyQ3 2026$55.1M+1%9.6%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Puma Biotechnology 8-K on SEC EDGAR · CIK 1401667 · Pharmaceutical Preparations

13F: who owns PBYI and who is buying

Largest holders of PBYI (13F)Largest holders of PBYI (13F)Acorn Capital Advisors, LLC$33.5MBlackRock$30.9MVanguard Group$22.6MAmerican Century Companies$18.8MAcadian Asset Management LLC$16.6MRenaissance Technologies LLC$14.9MVanguard Capital Management LLC$14.9MVanguard Portfolio Management LLC$14.8MDimensional Fund Advisors LP$12.3MGeode Capital Management, LLC$10.9M
Funds' net buying of PBYI by quarter (13F)Funds' net buying of PBYI by quarter (13F)−$4.0M2024-09−$11.1M2024-12$2.5M2025-03$6.4M2025-06$8.2M2025-09$6.4M2025-12$8.6M2026-03$2.9M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on PBYI

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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