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Spruce Biosciences vs Xenetic Biosciences: SPRB and XBIO compared
Spruce Biosciences is the larger company: $697K of revenue in its latest quarter (Q4 2024) against $661K for Xenetic Biosciences (Q2 2026). Xenetic Biosciences is growing faster (+12% against -76% a year earlier).
Where the money goes: SPRB and XBIO
Spruce Biosciences (SPRB) · Q4 2024
Spruce Biosciences, Q4 2024: revenue $697K (-76% year over year), net loss $23.6M, operating cash flow −$20.7M. The chart follows the revenue to costs, profit and cash.
Xenetic Biosciences (XBIO) · Q2 2026
Xenetic Biosciences, Q2 2026: revenue $661K (+12% year over year), operating margin -147.1%, net loss $930K, operating cash flow −$875K. The chart follows the revenue to costs, profit and cash.
| Spruce Biosciences (SPRB) | Xenetic Biosciences (XBIO) | |
|---|---|---|
| Latest quarter | Q4 2024 | Q2 2026 |
| Revenue | $697K | $661K |
| Revenue growth, Y/Y | -76% | +12% |
| Operating margin | n/m | -147.1% |
| Net earnings | −$23.6M | −$930K |
| Net margin | — | -140.7% |
| Operating cash flow | −$20.7M | −$875K |
Questions
Which is bigger, Spruce Biosciences or Xenetic Biosciences?
Spruce Biosciences is the larger company: $697K of revenue in its latest quarter (Q4 2024) against $661K for Xenetic Biosciences (Q2 2026).
Is Spruce Biosciences or Xenetic Biosciences growing faster?
Xenetic Biosciences is growing faster (+12% against -76% a year earlier).
More: Spruce Biosciences earnings · how Spruce Biosciences makes money · Xenetic Biosciences earnings · how Xenetic Biosciences makes money
From the companies' latest 10-Q, 10-K or earnings release (10-K filed Apr 15, 2025; 10-Q filed Aug 6, 2026). Fiscal quarters can end on different dates. Not investment advice.