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Veracyte vs Castle Biosciences: VCYT and CSTL compared
Veracyte is the larger company: $152M of revenue in its latest quarter (Q3 2026) against $103M for Castle Biosciences (Q3 2026). Castle Biosciences is growing faster (+24% against +15% a year earlier). Veracyte is more profitable, with an operating margin of 10.9% against -2.7%.
Where the money goes: VCYT and CSTL
Veracyte (VCYT) · Q3 2026
Veracyte, Q3 2026: revenue $152M (+15% year over year), operating margin 10.9%, net earnings $31.5M, operating cash flow $40.3M. The chart follows the revenue to costs, profit and cash.
Castle Biosciences (CSTL) · Q3 2026
Castle Biosciences, Q3 2026: revenue $103M (+24% year over year), operating margin -2.7%, net loss $4.1M, operating cash flow $19.7M. The chart follows the revenue to costs, profit and cash.
| Veracyte (VCYT) | Castle Biosciences (CSTL) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $152M | $103M |
| Revenue growth, Y/Y | +15% | +24% |
| Gross margin | 70.6% | — |
| Operating margin | 10.9% | -2.7% |
| Net earnings | $31.5M | −$4.1M |
| Net margin | 20.8% | -4.0% |
| Operating cash flow | $40.3M | $19.7M |
| Free cash flow | $37.9M | $12.2M |
| Market value | $3.7B | — |
| P/E | 32.4× | — |
| Analysts’ mean target | $57.40 | — |
Where the revenue comes from
Veracyte
- Testing revenue: $146M (96%)
- Product revenue: $4.6M (3%)
- Biopharmaceutical and other revenue: $709K (0%)
Castle Biosciences
- Non-Dermatologic: $55.0M (53%)
- Dermatologic: $47.9M (47%)
Questions
Which is bigger, Veracyte or Castle Biosciences?
Veracyte is the larger company: $152M of revenue in its latest quarter (Q3 2026) against $103M for Castle Biosciences (Q3 2026).
Is Veracyte or Castle Biosciences growing faster?
Castle Biosciences is growing faster (+24% against +15% a year earlier).
Which is more profitable, Veracyte or Castle Biosciences?
Veracyte is more profitable, with an operating margin of 10.9% against -2.7%.
More: Veracyte earnings · how Veracyte makes money · Castle Biosciences earnings · how Castle Biosciences makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 5, 2026; 10-Q filed Nov 5, 2026). Fiscal quarters can end on different dates. Not investment advice.