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Vanda Pharmaceuticals vs Opko Health: VNDA and OPK compared

Vanda Pharmaceuticals is the larger company: $69.8M of revenue in its latest quarter (Q3 2026) against $65.4M for Opko Health (Q3 2026). Vanda Pharmaceuticals is growing faster (+24% against +16% a year earlier). Vanda Pharmaceuticals is more profitable, with an operating margin of -33.7% against -48.0%.

Vanda Pharmaceuticals vs Opko Health, latest quarterVanda Pharmaceuticals vs Opko Health, latest quarterVanda Pharmaceuticals (VNDA)Opko Health (OPK)Revenue$69.8M$65.4MRevenue growth, Y/Y+24%+16%Operating margin-33.7%-48.0%Net margin-32.3%-81.8%

Where the money goes: VNDA and OPK

Vanda Pharmaceuticals (VNDA) · Q3 2026

Vanda Pharmaceuticals, Q3 2026: revenue $69.8M (+24% year over year), operating margin -33.7%, net loss $22.6M, operating cash flow −$28.4M. The chart follows the revenue to costs, profit and cash.

Opko Health (OPK) · Q3 2026

Opko Health, Q3 2026: revenue $65.4M (+16% year over year), operating margin -48.0%, net loss $53.5M, operating cash flow −$36.3M. The chart follows the revenue to costs, profit and cash.

Vanda Pharmaceuticals revenue by segment, Q3 2026Vanda Pharmaceuticals revenue by segment, Q3 2026Fanapt®$38.8MHETLIOZ® net product sales$21.7MPONVORY® net product sales$7.7MNEREUSTM$1.6M
Opko Health revenue by segment, Q3 2026Opko Health revenue by segment, Q3 2026Product$41.8MLicense and Service$23.6M
Vanda Pharmaceuticals (VNDA)Opko Health (OPK)
Latest quarterQ3 2026Q3 2026
Revenue$69.8M$65.4M
Revenue growth, Y/Y+24%+16%
Operating margin-33.7%-48.0%
Net earnings−$22.6M−$53.5M
Net margin-32.3%-81.8%
Operating cash flow−$28.4M−$36.3M

Where the revenue comes from

Vanda Pharmaceuticals

Opko Health

Questions

Which is bigger, Vanda Pharmaceuticals or Opko Health?

Vanda Pharmaceuticals is the larger company: $69.8M of revenue in its latest quarter (Q3 2026) against $65.4M for Opko Health (Q3 2026).

Is Vanda Pharmaceuticals or Opko Health growing faster?

Vanda Pharmaceuticals is growing faster (+24% against +16% a year earlier).

Which is more profitable, Vanda Pharmaceuticals or Opko Health?

Vanda Pharmaceuticals is more profitable, with an operating margin of -33.7% against -48.0%.

More: Vanda Pharmaceuticals earnings · how Vanda Pharmaceuticals makes money · Opko Health earnings · how Opko Health makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Oct 29, 2026; 10-Q filed Nov 4, 2026). Fiscal quarters can end on different dates. Not investment advice.