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Zymeworks vs Equillium: ZYME and EQ compared

Zymeworks is the larger company: $4.6M of revenue in its latest quarter (Q2 2026) against $4.4M for Equillium (Q4 2024). Equillium is growing faster (-52% against -91% a year earlier). Equillium is more profitable, with an operating margin of -107.0% against -919.0%.

Zymeworks vs Equillium, latest quarterZymeworks vs Equillium, latest quarterZymeworks (ZYME)Equillium (EQ)Revenue$4.6M$4.4MRevenue growth, Y/Y-91%-52%Operating margin-919.0%-107.0%Net margin-980.8%-131.9%

Where the money goes: ZYME and EQ

Zymeworks (ZYME) · Q2 2026

Zymeworks, Q2 2026: revenue $4.6M (-91% year over year), operating margin -919.0%, net loss $45.0M, operating cash flow −$31.9M. The chart follows the revenue to costs, profit and cash.

Equillium (EQ) · Q4 2024

Equillium, Q4 2024: revenue $4.4M (-52% year over year), operating margin -107.0%, net loss $5.8M, operating cash flow −$3.3M. The chart follows the revenue to costs, profit and cash.

Zymeworks (ZYME)Equillium (EQ)
Latest quarterQ2 2026Q4 2024
Revenue$4.6M$4.4M
Revenue growth, Y/Y-91%-52%
Operating margin-919.0%-107.0%
Net earnings−$45.0M−$5.8M
Net margin-980.8%-131.9%
Operating cash flow−$31.9M−$3.3M
Market value$1.9B—
Analysts’ mean target$41.50—

Questions

Which is bigger, Zymeworks or Equillium?

Zymeworks is the larger company: $4.6M of revenue in its latest quarter (Q2 2026) against $4.4M for Equillium (Q4 2024).

Is Zymeworks or Equillium growing faster?

Equillium is growing faster (-52% against -91% a year earlier).

Which is more profitable, Zymeworks or Equillium?

Equillium is more profitable, with an operating margin of -107.0% against -919.0%.

More: Zymeworks earnings · how Zymeworks makes money · Equillium earnings · how Equillium makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Aug 6, 2026; 10-K filed Mar 27, 2025). Fiscal quarters can end on different dates. Not investment advice.