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Pharmaceutical Preparations: capital spending and supply chain

SIC 2834 · 169 companies with filed cash-flow statements

Capital spending, 12 months$33.3B
Operating cash flow$145.5B
Capex / cash flow23%
Capex / revenue5.1%
Top 3 share62%

Analysis

169 companies in Pharmaceutical Preparations (SIC 2834) spent $33.3B on capital projects over their latest twelve months, 23% of the $145.5B their operations generated; the three largest spenders — LLY, JNJ, MRK — account for 62%.

Capital spending is 5.1% of the industry's $648.0B of annual revenue.

By the industry's asset mix most of it goes to equipment (44%); about $5.1B is imported.

The largest supplier of that spending is manufacturing structures ($8.4B).

Its largest supplying industries, by the input-output tables: imports ($77.8B), drugs and druggists' sundries ($53.9B), biological product (except diagnostic) manufacturing ($40.1B).

Charts

Pharmaceutical Preparations: capital spending by company, latest twelve monthsPharmaceutical Preparations: capital spending by company, latest twelve monthsLLY$11.0BJNJ$5.6BMRK$4.0BPFE$2.4BABT$2.1BBMY$1.4BABBV$1.2BREGN$1.0BUTHR$562MTEVA$535MZTS$493MVRTX$492M
Filed cash-flow statements (SEC XBRL).
Pharmaceutical Preparations: what the capital spending buys (US part)Pharmaceutical Preparations: what the capital spending buys (US part)Structures$8.7BEquipment$10.8BSoftware$3.3BOther$1.8B
Capital spending × the industry’s asset mix (BEA fixed assets): grade C, an industry average applied to filed figures.
Pharmaceutical Preparations: the industries that build and sell what it buysPharmaceutical Preparations: the industries that build and sell what it buysManufacturing structures$8.4BSoftware publishers$1.8BMaterial handling equipment manuf…$1.4BOther industrial machinery manufa…$1.3BAir conditioning, refrigeration, …$1.3BOther general purpose machinery m…$880MMeasuring, dispensing, and other …$793MAir and gas compressor manufactur…$741MPlate work and fabricated structu…$679MCustom computer programming servi…$666M
BEA fixed assets: investment by asset type → supplying industry. Estimates (grade C).
Pharmaceutical Preparations: its first-tier supplying industriesPharmaceutical Preparations: its first-tier supplying industriesImports$77.8BDrugs and druggists' sundries$53.9BBiological product (except diagno…$40.1BManagement of companies and enter…$25.5BMedicinal and botanical manufactu…$18.3BLegal services$8.0BPharmaceutical preparation manufa…$7.3BOther real estate$7.1BManagement consulting services$4.5BMonetary authorities and deposito…$3.1B
Purchased inputs × the industry’s input mix (BEA Use table), US part: grade C.
Pharmaceutical Preparations: where the industry's cash came from (+) and went (−)Pharmaceutical Preparations: where the industry's cash came from (+) and went (−)Operating cash flow$163.0BOther investing (out)−$78.9BDividends−$59.9BOther financing (in)$53.7BNet borrowing$41.7BAcquisitions−$38.6BCapital spending−$33.1BBuybacks−$33.0BCash drawn from the balance s…$30.8BCash added to the balance she…−$19.9BNet debt repaid−$19.6BOperating cash outflow−$13.2BOther investing (in)$8.7BOther financing (out)−$8.2B
The companies’ cash-flow statements, latest four quarters or fiscal year: every figure filed (grade A).

Capital spending by company

CompanyCapital spendingOperating cash flowCapex / OCFPeriod
LLY ELI Lilly$11.0B$30.6B36%TTM to Q3 2026
JNJ Johnson & Johnson$5.6B$26.2B21%TTM to Q3 2026
MRK Merck$4.0B$18.7B21%TTM to Q3 2026
PFE Pfizer$2.4B$14.2B17%TTM to Q3 2026
ABT Abbott Laboratories$2.1B$8.9B24%TTM to Q3 2026
BMY Bristol Myers Squibb$1.4B$10.7B13%TTM to Q3 2026
ABBV AbbVie$1.2B$20.1B6%TTM to Q3 2026
REGN Regeneron Pharmaceuticals$1.0B$4.8B21%TTM to Q3 2026
UTHR United Therapeutics$562M$1.4B39%TTM to Q3 2026
TEVA Teva Pharmaceutical Industries$535M$1.8B30%TTM to Q3 2026
ZTS Zoetis$493M$2.7B18%TTM to Q3 2026
VRTX Vertex Pharmaceuticals$492M$3.7B13%TTM to Q3 2026
VTRS Viatris$375M$2.5B15%TTM to Q3 2026
BHC Bausch Health Companies$344M$2.2B16%TTM to Q3 2026
ELAN Elanco Animal Health$206M$614M34%TTM to Q3 2026
OGN Organon$168M$843M20%TTM to Q3 2026
ALNY Alnylam Pharmaceuticals$150M$956M16%TTM to Q3 2026
VREOF Vireo Growth$143M$26.2M544%TTM to Q2 2026
ONC BeOne Medicines$141M$1.6B9%TTM to Q3 2026
BMRN BioMarin Pharmaceutical$119M$677M18%TTM to Q3 2026
AMRX Amneal Pharmaceuticals$72.9M$201M36%TTM to Q2 2026
PRGO Perrigo$72.4M$241M30%TTM to Q3 2026
JAZZ Jazz Pharmaceuticals$70.8M$1.7B4%TTM to Q3 2026
INDV Indivior Pharmaceuticals$65.0M$96.0M68%TTM to Q3 2026
IONS Ionis Pharmaceuticals$64.4M−$496M—TTM to Q2 2026
PAHC Phibro Animal Health$64.1M$85.7M75%TTM to Q1 FY27
Keenova Therapeutics$47.6M$245M19%TTM to Q2 2026
AMPH Amphastar Pharmaceuticals$36.3M$175M21%TTM to Q3 2026
INSM Insmed$32.0M−$596M—TTM to Q3 2026
CYRX Cryoport$29.8M$11.0M271%TTM to Q3 2026
ABCL AbCellera Biologics$24.7M−$94.9M—TTM to Q2 2026
ANIP ANI Pharmaceuticals$23.9M$229M10%TTM to Q3 2026
LQDA Liquidia$17.0M$168M10%TTM to Q2 2026
OCUL Ocular Therapeutix$16.9M−$238M—TTM to Q2 2026
CYTK Cytokinetics$16.6M−$572M—TTM to Q3 2026
ARWR Arrowhead Pharmaceuticals$16.1M−$59.1M—TTM to Q3 FY26
ALKS Alkermes$15.6M$243M6%TTM to Q3 2026
PBH Prestige Consumer Healthcare$15.6M$230M7%TTM to Q2 FY27
ACAD Acadia Pharmaceuticals$15.5M$97.5M16%TTM to Q3 2026
MNKD Mannkind$12.2M−$66.2M—TTM to Q3 2026
EBS Emergent BioSolutions$11.7M$200M6%TTM to Q3 2026
MDGL Madrigal Pharmaceuticals$11.6M−$157M—TTM to Q3 2026
CAPR Capricor Therapeutics$10.9M−$104M—TTM to Q2 2026
ORGO Organogenesis Holdings$10.4M$10.3M101%TTM to Q3 2026
IMNM Immunome$10.3M−$209M—TTM to Q2 2026
OPK Opko Health$10.3M−$125M—TTM to Q3 2026
NRIX Nurix Therapeutics$9.5M$379M3%TTM to Q3 FY26
SRPT Sarepta Therapeutics$9.2M$186M5%TTM to Q3 2026
NATR Natures Sunshine Products$9.1M$19.6M46%TTM to Q3 2026
PTCT PTC Therapeutics$8.4M$10.5M80%TTM to Q3 2026
MRVI Maravai Lifesciences Holdings$8.2M−$5.1M—TTM to Q3 2026
PCRX Pacira BioSciences$7.9M$177M4%TTM to Q3 2026
KURA Kura Oncology$5.7M−$112M—TTM to Q2 2026
STOK Stoke Therapeutics$5.4M−$210M—TTM to Q3 2026
TNXP Tonix Pharmaceuticals Holding$5.1M−$153M—TTM to Q2 2026
ABEO Abeona Therapeutics$5.1M−$76.4M—TTM to Q2 2026
RARE Ultragenyx Pharmaceutical$5.0M−$437M—TTM to Q3 2026
ROIV Roivant Sciences$4.6M−$816M—TTM to Q1 FY27
AGIO Agios Pharmaceuticals$4.3M−$332M—TTM to Q3 2026
SDGR Schrodinger$4.2M−$113M—TTM to Q3 2026

Customers and suppliers named in annual reports

SupplierCustomerShare of supplier revenueEvidenceSource
BMYMCK36%Stated in 10-K (XBRL)filing
PFEMCK25%Stated in 10-K (XBRL)filing
BMYCOR29%Stated in 10-K (XBRL)filing
BMYCAH22%Stated in 10-K (XBRL)filing
PFECOR16%Stated in 10-K (XBRL)filing
PFECAH13%Stated in 10-K (XBRL)filing
BHCCOR18%Stated in 10-K (customer table)filing
BHCMCK16%Stated in 10-K (customer table)filing
BHCCAH14%Stated in 10-K (customer table)filing
ONCMCK18%Stated in 10-K (XBRL)filing
ALNYNVS23%Stated in 10-K (customer table)filing
Keenova Therapeutics plcCOR48%Stated in 10-K (customer table)filing
Keenova Therapeutics plcFFF Enterprises, Inc46%Stated in 10-K (XBRL)filing
ELANCOR12%Stated in 10-K (sentence)filing
ALKSMCK38%Stated in 10-K (sentence)filing
PRGOWMT12%Stated in 10-K (sentence)filing
ALKSMc Kesson Corporation31%Stated in 10-K (XBRL)filing
JAZZMCK10%Stated in 10-K (customer table)filing
ALNYREGN11%Stated in 10-K (customer table)filing
HRMYCVS38%Stated in 10-K (sentence)filing
HRMYAccredo Health Group, Inc36%Stated in 10-K (XBRL)filing
IRWDABBV99%Stated in 10-K (XBRL)filing
ALKSCOR18%Stated in 10-K (sentence)filing
HRMYPANTHERx Specialty Pharmacy LLC26%Stated in 10-K (XBRL)filing
PCRXMCK31%Stated in 10-K (sentence)filing
ALKSCAH15%Stated in 10-K (sentence)filing
PBHWMT20%Stated in 10-K (sentence)filing
PCRXCAH26%Stated in 10-K (sentence)filing
ITGRABT10%Stated in 10-K (sentence)filing
AMPHMCK24%Stated in 10-K (XBRL)filing
PBHAMZN15%Stated in 10-K (sentence)filing
PCRXCOR22%Stated in 10-K (sentence)filing
AMPHCOR22%Stated in 10-K (XBRL)filing
AMPHCAH19%Stated in 10-K (XBRL)filing
RIGLMCK42%Stated in 10-K (customer table)filing
EXELRPRX3%Stated in 10-K (sentence)filing
GYRESinopharm Group Company Limited52%Stated in 10-K (XBRL)filing
AKBADVA25%Stated in 10-K (customer table)filing
ANIKJNJ50%Stated in 10-K (sentence)filing
RIGLCOR19%Stated in 10-K (customer table)filing

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Evidence grades: A filed figure · B computed from filed figures · C industry average (BEA input-output and fixed-asset tables) applied to filed figures. Estimates are not the companies’ own records. Not investment advice.