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Ionis Pharmaceuticals (IONS) earnings on Nov 9, 2026: what to expect

Ionis Pharmaceuticals (IONS) is expected to report earnings on Nov 9, 2026, tomorrow, for the quarter ending Sep 30, 2026. Analysts expect EPS of −$0.93 (−$1.08 to −$0.65, 9 estimates) on revenue of $184M, against −$0.61 and $157M a year ago. It beat the EPS estimate in 100% of the quarters on record; Filing Flows' model gives it a 84% chance of beating next time.

Report dateNov 9, 2026
Days to go1
EPS estimate−$0.93
Revenue estimate$184M
Beat rate100%

What to watch

Last quarter (Q2 2026) the lines that make up revenue grew like this; the report shows whether the trend holds:

Ionis Pharmaceuticals: revenue lines, growth year over year, Q2 2026Ionis Pharmaceuticals: revenue lines, growth year over year, Q2 2026Revenue-41%Research and Development Reve…+23%Commercial+15%Royalty+9%Spinraza Royalties-2%Product+62%

Filing Flows' own estimate from the SEC figures — the same quarter last year times recent growth — is EPS −$0.61 on revenue of $198M, against the analysts' −$0.93.

The last report

Ionis Pharmaceuticals reported revenue of $268M for the second quarter 2026 (-41% Y/Y), net loss $115M: Research and Development Revenue $150M, Royalty $76.0M, DAWNZERASales $26.6M, Other Commercial $11.5M. How it makes money → · Every quarter →

Ionis Pharmaceuticals: EPS against the estimate, last 4 reportsIonis Pharmaceuticals: EPS against the estimate, last 4 reportsEstimateReported−$1.05−$0.61Oct 25−$1.22−$1.15Feb 26−$0.78−$0.30Apr 26−$0.88−$0.42Jul 26
Latest (Jul 26): Estimate −$0.88, Reported −$0.42.
IONS: the stock's move on each reportIONS: the stock's move on each reportJul 29, 2026-3.7%Apr 29, 2026+4.2%Feb 25, 2026-5.7%Oct 29, 2025+0.8%

Ionis Pharmaceuticals' latest quarter

Ionis Pharmaceuticals, Q2 2026: revenue $268M (-41% year over year), operating margin -38.2%, net loss $115M, operating cash flow $566M. The chart follows the revenue to costs, profit and cash.

Questions

When does IONS report earnings?

Ionis Pharmaceuticals is expected to report on Nov 9, 2026.

What are analysts expecting from Ionis Pharmaceuticals?

EPS of −$0.93 and revenue of $184M for the quarter.

Does Ionis Pharmaceuticals usually beat earnings?

It beat the consensus EPS estimate in 100% of the quarters on record.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.