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BeOne Medicines (ONC) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 5, 2026 · BeOne Medicines (ONC) Q3 2026 earnings results →

Q3 2026 Revenue up 34% year over year to $1.9B · 20¢ of every $1 of revenue kept as net profit · operating margin 22.2%

BeOne Medicines made $1.9B in Q3 2026 (+34% Y/Y): Product revenue, net $1.9B, BAITUOWEI $22.1M, POBEVCY $10.7M. Operating margin 22.2%, net earnings $385M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 5, 2026.

Revenue$1.9B
Year over year+34%
Operating margin22.2%
Net earnings$385M
Operating cash flow$509M

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BeOne Medicines Q3 2026 revenue breakdown: Sankey diagram of revenue (Product revenue, net, BAITUOWEI, POBEVCY), costs, profit and cash flow
BeOne Medicines Q3 2026 revenue breakdown — free to use with credit and a link (terms). Share on X
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What changed this quarter

Revenue was $1.9B in Q3 2026, up 34% year over year and up 11% from the previous quarter. BRUKINSA was the largest line at 74% of revenue. BRUKINSA added $0.35B year over year (up 34%), 73% of the total change. KYPROLIS declined 24%.

Gross margin was 88.5%, up 2.4 points from Q3 2025. Operating profit was $0.42B, a 22.2% margin (up 10.6 points year over year). Of the extra revenue versus Q3 2025, 54% reached operating profit, above the 12% margin then. Operating expenses grew 19% against revenue growth of 34%. The fastest-growing cost line was Research & development (+26%). Net earnings were $0.38B, up 208% year over year. The effective tax rate was 6.3%.

Operating cash flow was $0.51B (up 26% year over year), 132% of net earnings. Non-cash charges added back $0.06B of depreciation and amortization and $0.13B of share-based compensation. Working capital and other items used $0.07B. Capital expenditures of $0.04B left free cash flow of $0.47B.

Quarterly history

BeOne Medicines revenue by quarterBeOne Medicines revenue by quarter$1.1BQ1 2025$1.3BQ2 2025$1.4BQ3 2025$1.5BQ4 2025$1.5BQ1 2026$1.7BQ2 2026$1.9BQ3 2026
BeOne Medicines net earnings by quarterBeOne Medicines net earnings by quarter$1.3MQ1 2025$94.3MQ2 2025$125MQ3 2025$66.5MQ4 2025$227MQ1 2026$237MQ2 2026$385MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 5, 2026$1.9B+34%22.2%$385M$509M
Q2 202610-QAug 5, 2026$1.7B+30%19.1%$237M$463M
Q1 202610-QMay 6, 2026$1.5B+36%16.5%$227M$201M
Q4 202510-KFeb 26, 2026$1.5B+33%12.4%$66.5M$417M
Q3 202510-QNov 6, 2025$1.4B+41%11.5%$125M$403M
Q2 202510-QAug 6, 2025$1.3B+42%6.7%$94.3M$264M
Q1 202510-QMay 7, 2025$1.1B+49%1.0%$1.3M$44.1M

Charts

BeOne Medicines: revenue growth, year over year and quarter over quarterBeOne Medicines: revenue growth, year over year and quarter over quarterY/YQ/Q+49%Q1 2025+42%+18%Q2 2025+41%+7%Q3 2025+33%+6%Q4 2025+36%+1%Q1 2026+30%+13%Q2 2026+34%+11%Q3 2026
Latest (Q3 2026): Y/Y +34%, Q/Q +11%.
BeOne Medicines: where the cash came from (+) and went (−), TTM to Q3 2026BeOne Medicines: where the cash came from (+) and went (−), TTM to Q3 2026Cash drawn (+) / kept (−)−$1.8BOperating cash flow$1.6BOther financing$843MNet borrowing (+) / repaid (−)−$746MShares issued$164MCapital spending−$141MExchange rates$72.8MOther investing−$28.0M
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
BeOne Medicines: profit against cash, quarter by quarterBeOne Medicines: profit against cash, quarter by quarterNet incomeOperating cash flow−$152M$75.2MQ4 2024$1.3M$44.1MQ1 2025$94.3M$264MQ2 2025$125M$403MQ3 2025$66.5M$417MQ4 2025$227M$201MQ1 2026$237M$463MQ2 2026$385M$509MQ3 2026
Latest (Q3 2026): Net income $385M, Operating cash flow $509M.
BeOne Medicines: diluted shares by fiscal yearBeOne Medicines: diluted shares by fiscal year1.09BFY20201.21BFY20211.34BFY20221.36BFY20231.37BFY20241.47BFY2025
+35.9% since FY2020: more shares outstanding (issuance, stock pay).
BeOne Medicines in its industry: growth against margin (225 companies, SIC 2834)BeOne Medicines in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMONC (+34%, 22%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

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Customers and suppliers named in filings

Sells to

About BeOne Medicines

We are a leading global oncology company discovering and developing innovative treatments that are more accessible to cancer patients worldwide. In 2025, we generated total global revenue of approximately $5.3 billion, increasing revenue by approximately 40.2% from the prior year, while achieving net income of $286.9 million, net cash provided by operating activities of $1.1 billion and positive free cash flow of $941.7 million. We are serial innovators in hematology and have built a differentiated, wholly-owned, and foundational franchise. We are the only company with potentially best-in-class assets across three foundational chronic lymphocytic leukemia (“CLL”) mechanisms of action (“MoAs”).

In its own words, from its 10-K, filed Feb 26, 2026.

BeOne Medicines against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +34% against the peers' median +10%. Operating margin: 22.2% against the peers' median 22.2%.

CompanyQuarterRevenueY/YOp. margin
ONC BeOne MedicinesQ3 2026$1.9B+34%22.2%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: BeOne Medicines 10-Q on SEC EDGAR · CIK 1651308 · Pharmaceutical Preparations

Guidance and outlook

BeOne Medicines Revenue: guidance against what was reportedBeOne Medicines Revenue: guidance against what was reportedguided rangereported (above / within / below)FY2025$5.3BFY2026
Met or beat 1 of 1 guided periods. Grey: the last range guided before the figures came out; dot: the reported figure.
BeOne Medicines GAAP gross margin: guidance against what was reportedBeOne Medicines GAAP gross margin: guidance against what was reportedguided rangereported (above / within / below)FY202587.5%FY2026
Met or beat 1 of 1 guided periods. Grey: the last range guided before the figures came out; dot: the reported figure.
BeOne Medicines: what its forward-looking statements are about (10-Q filed 2026-11-05)BeOne Medicines: what its forward-looking statements are about (10-Q filed 2026-11-05)Other7Tax3Costs1Financing1Demand1
13 statements; tone +0.15 (−1 all cautious, +1 all confident); 2 hedged.
BeOne Medicines: outlook statements against the filing beforeBeOne Medicines: outlook statements against the filing beforeConfident2

13F: who owns ONC and who is buying

Largest holders of ONC (13F)Largest holders of ONC (13F)Baker Bros. Advisors LP$2.5BPrimecap Management$1.4BCapital International Investors$1.2BFMR LLC$706MCapital World Investors$641MCitadel Advisors LLC$406MPrice T Rowe Associates$216MBlackRock$198MMillennium Management LLC$155MMorgan Stanley$142M
Funds' net buying of ONC by quarter (13F)Funds' net buying of ONC by quarter (13F)−$425M2024-09−$475M2024-12−$321M2025-03−$1.9B2025-06−$478M2025-09$277M2025-12$253M2026-03$10.0M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on ONC

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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