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Filing Flows › Prelude Therapeutics (PRLD) › Q1 2026 › vs Q4 2025

Prelude Therapeutics (PRLD) Q1 2026 vs Q4 2025 (quarter over quarter)

Prelude Therapeutics's revenue fell $1.1M (-19%) from $5.6M in Q4 2025 to $4.6M in Q1 2026.

Prelude Therapeutics, Q1 2026: revenue $4.6M, operating margin -309.5%, net loss $10.4M, operating cash flow −$21.7M. The chart draws each line against Q4 2025, the increases inside each band.

Prelude Therapeutics: what changed, Q1 2026 vs Q4 2025Prelude Therapeutics: what changed, Q1 2026 vs Q4 2025Working capital & other$51.0MOperating cash sources$44.9MCash used in operations$44.8MNet loss−$6.1MNet loss absorbed−$6.1MResearch & development−$4.4MCosts & expenses−$4.2MOperating costs−$4.2MOther income, net$2.9MGeneral & admin$160K

Every line

LineQ1 2026Q4 2025Change%
Revenue$4.6M$5.6M−$1.1M-19%
Other income, net$3.8M$891K$2.9M+326%
Net loss$10.4M$16.5M−$6.1M-37%
Costs & expenses$18.8M$23.0M−$4.2M-18%
Operating costs$18.8M$23.0M−$4.2M-18%
Research & development$13.6M$18.0M−$4.4M-24%
General & admin$5.2M$5.0M$160K+3%
Operating cash sources$24.1M−$20.9M$44.9M—
Depreciation & amortization$391K$418K−$27K-6%
Share-based compensation$2.0M$1.8M$156K+8%
Cash used in operations$21.7M−$23.1M$44.8M—
Net loss absorbed$10.4M$16.5M−$6.1M-37%
Working capital & other$13.7M−$37.3M$51.0M—

Questions

How much did Prelude Therapeutics's revenue grow quarter over quarter in Q1 2026?

Prelude Therapeutics's revenue fell $1.1M (-19%) from $5.6M in Q4 2025 to $4.6M in Q1 2026.

Q1 2026 results → · Compare in the interactive Sankey →