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Prelude Therapeutics (PRLD) Q2 2026 earnings results (second quarter 2026)

10-Q filed Aug 11, 2026

Prelude Therapeutics (PRLD) reported revenue of $5.7M for the second quarter 2026 (Q2 2026) and +25% from the quarter before. Operating margin was -270.9%, net loss $13.9M (244.1% of revenue).

Revenue$5.7M
Year over year—
Quarter over quarter+25%
Operating margin-270.9%
Net earnings−$13.9M

Prelude Therapeutics, Q2 2026: revenue $5.7M, operating margin -270.9%, net loss $13.9M, operating cash flow −$15.6M. The chart follows the revenue to costs, profit and cash.

Q2 2026AmountQ/QY/Y
Revenue$5.7M+25%—
Operating profit−$15.5M——
Net earnings−$13.9M——
Operating cash flow−$15.6M——

What changed

Revenue was $5.7M in Q2 2026, up 25% from the previous quarter.

Operating costs exceeded revenue by $15.5M, an operating margin of -270.9%. The quarter ended with a net loss of $13.9M, wider than the previous quarter's $10.4M loss.

Operating cash flow was −$15.6M. Non-cash charges added back $353K of depreciation and amortization and $2.0M of share-based compensation. Working capital and other items used $4.0M.

Questions

What was Prelude Therapeutics' revenue in the second quarter 2026?

Prelude Therapeutics (PRLD) reported revenue of $5.7M for the second quarter 2026 (Q2 2026) and +25% from the quarter before.

Was Prelude Therapeutics profitable in the second quarter 2026?

Operating loss was $15.5M (-270.9% of revenue) and net loss $13.9M.

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Source: Prelude Therapeutics 10-Q on SEC EDGAR.