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Personalis (PSNL) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 7, 2026

Personalis (PSNL) reported revenue of $15.5M for the first quarter 2026 (Q1 2026), -25% from a year earlier and -11% from the quarter before. Operating margin was -207.9%, net loss $30.0M (194.1% of revenue).

Revenue$15.5M
Year over year-25%
Quarter over quarter-11%
Operating margin-207.9%
Net earnings−$30.0M

Personalis, Q1 2026: revenue $15.5M (-25% year over year), operating margin -207.9%, net loss $30.0M, operating cash flow −$22.5M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$15.5M-11%-25%
Operating profit−$32.2M——
Net earnings−$30.0M——
Operating cash flow−$22.5M——

What changed

Revenue was $15.5M in Q1 2026, down 25% year over year and down 11% from the previous quarter.

Operating costs exceeded revenue by $32.2M, an operating margin of -207.9%. Total costs grew 24% against a revenue fall of 25%. The fastest-growing cost line was SG&A (+46%). The quarter ended with a net loss of $30.0M, wider than the previous quarter's $23.8M loss.

Operating cash flow was −$22.5M. Non-cash charges added back $2.4M of depreciation and amortization and $2.6M of share-based compensation. Working capital and other items added $2.6M. Capital expenditures of $3.2M exceeded it, leaving free cash flow of −$25.7M.

Questions

What was Personalis' revenue in the first quarter 2026?

Personalis (PSNL) reported revenue of $15.5M for the first quarter 2026 (Q1 2026), -25% from a year earlier and -11% from the quarter before.

Was Personalis profitable in the first quarter 2026?

Operating loss was $32.2M (-207.9% of revenue) and net loss $30.0M.

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Source: Personalis 10-Q on SEC EDGAR.