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Rhythm Pharmaceuticals (RYTM) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 3, 2026 · Rhythm Pharmaceuticals (RYTM) Q3 2026 earnings results →

Q3 2026 Revenue up 80% year over year to $92.1M · 45¢ of every $1 of revenue lost · operating margin -42.6%

Rhythm Pharmaceuticals made $92.1M in Q3 2026 (+80% Y/Y). Operating margin -42.6%, net loss $41.4M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 3, 2026.

Revenue$92.1M
Year over year+80%
Operating margin-42.6%
Net earnings−$41.4M
Operating cash flow−$3.1M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $92.1M in Q3 2026, up 80% year over year and up 29% from the previous quarter.

Operating costs exceeded revenue by $39.3M, an operating margin of -42.6%. Total costs grew 26% against revenue growth of 80%. The fastest-growing cost line was Cost of revenue (+121%). The quarter ended with a net loss of $41.4M, narrower than the previous quarter's $49.3M loss.

Operating cash flow was −$3.1M. Non-cash charges added back $25.0M of share-based compensation. Working capital and other items added $13.3M.

Quarterly history

Rhythm Pharmaceuticals revenue by quarterRhythm Pharmaceuticals revenue by quarter$32.7MQ1 2025$48.5MQ2 2025$51.3MQ3 2025$57.3MQ4 2025$60.1MQ1 2026$71.3MQ2 2026$92.1MQ3 2026
Rhythm Pharmaceuticals net earnings by quarterRhythm Pharmaceuticals net earnings by quarter−$49.5MQ1 2025−$46.6MQ2 2025−$52.9MQ3 2025−$47.5MQ4 2025−$55.6MQ1 2026−$49.3MQ2 2026−$41.4MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 3, 2026$92.1M+80%-42.6%−$41.4M−$3.1M
Q2 202610-QAug 4, 2026$71.3M+47%-68.1%−$49.3M−$9.2M
Q1 202610-QMay 5, 2026$60.1M+84%-87.1%−$55.6M−$44.2M
Q4 202510-KFeb 26, 2026$57.3M+37%-82.2%−$47.5M−$25.4M
Q3 202510-QNov 4, 2025$51.3M+54%-102.6%−$52.9M−$26.6M
Q2 202510-QAug 5, 2025$48.5M+67%-93.4%−$46.6M−$23.3M
Q1 202510-QMay 7, 2025$32.7M+26%-143.7%−$49.5M−$40.4M

Charts

Rhythm Pharmaceuticals: revenue growth, year over year and quarter over quarterRhythm Pharmaceuticals: revenue growth, year over year and quarter over quarterY/YQ/Q+26%Q1 2025+67%+48%Q2 2025+54%+6%Q3 2025+37%+12%Q4 2025+84%+5%Q1 2026+47%+19%Q2 2026+80%+29%Q3 2026
Latest (Q3 2026): Y/Y +80%, Q/Q +29%.
Rhythm Pharmaceuticals: where the cash came from (+) and went (−), TTM to Q3 2026Rhythm Pharmaceuticals: where the cash came from (+) and went (−), TTM to Q3 2026Other investing$86.8MOperating cash flow−$81.8MNet borrowing (+) / repaid (−)−$24.5MShares issued$22.3MOther financing−$13.5MCash drawn (+) / kept (−)$11.5MCapital spending−$1.5MExchange rates$756K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Rhythm Pharmaceuticals: profit against cash, quarter by quarterRhythm Pharmaceuticals: profit against cash, quarter by quarterNet incomeOperating cash flow−$43.3M−$18.8MQ4 2024−$49.5M−$40.4MQ1 2025−$46.6M−$23.3MQ2 2025−$52.9M−$26.6MQ3 2025−$47.5M−$25.4MQ4 2025−$55.6M−$44.2MQ1 2026−$49.3M−$9.2MQ2 2026−$41.4M−$3.1MQ3 2026
Latest (Q3 2026): Net income −$41.4M, Operating cash flow −$3.1M.
Rhythm Pharmaceuticals: diluted shares by fiscal yearRhythm Pharmaceuticals: diluted shares by fiscal year44MFY202050MFY202152MFY202258MFY202361MFY202465MFY2025
+47.3% since FY2020: more shares outstanding (issuance, stock pay).
Rhythm Pharmaceuticals in its industry: growth against margin (225 companies, SIC 2834)Rhythm Pharmaceuticals in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMRYTM (+80%, -43%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Rhythm Pharmaceuticals

We are a global, commercial-stage biopharmaceutical company dedicated to transforming the lives of patients living with rare neuroendocrine diseases. We are focused on advancing melanocortin-4 receptor (MC4R) agonists, including our lead asset, IMCIVREE ® (setmelanotide), as precision medicines designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. While obesity affects hundreds of millions of people worldwide, we are developing therapies for a subset of individuals who have hyperphagia, a pathological, insatiable hunger and impaired satiety accompanied by persistent and abnormal food-seeking behaviors, decreased energy expenditure and severe obesity due to diseases such as acquired or congenital hypothalamic obesity, Bardet-Biedl syndrome (BBS), Prader-Willi syndrome (PWS) and other diseases caused by impaired MC4R pathway signaling.

In its own words, from its 10-K, filed Feb 26, 2026.

Rhythm Pharmaceuticals against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +80% against the peers' median +10%. Operating margin: -42.6% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
RYTM Rhythm PharmaceuticalsQ3 2026$92.1M+80%-42.6%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Rhythm Pharmaceuticals 10-Q on SEC EDGAR · CIK 1649904 · Pharmaceutical Preparations

Guidance and outlook

Rhythm Pharmaceuticals: what its forward-looking statements are about (10-Q filed 2026-11-03)Rhythm Pharmaceuticals: what its forward-looking statements are about (10-Q filed 2026-11-03)Costs9Other7Demand6Financing2Supply chain1
25 statements; tone +0.28 (−1 all cautious, +1 all confident); 5 hedged.
Rhythm Pharmaceuticals: outlook statements against the filing beforeRhythm Pharmaceuticals: outlook statements against the filing beforeConfident8Cautious1

13F: who owns RYTM and who is buying

Largest holders of RYTM (13F)Largest holders of RYTM (13F)RA Capital Management, L.P.$740MBlackRock$684MVanguard Group$665MBaker Bros. Advisors LP$622MPrimecap Management$352MVanguard Portfolio Management LLC$348MVanguard Capital Management LLC$334MPerceptive Advisors LLC$287MState Street$286MPrice T Rowe Associates$285M
Funds' net buying of RYTM by quarter (13F)Funds' net buying of RYTM by quarter (13F)−$6.7M2024-09−$64.5M2024-12−$8.2M2025-03$71.8M2025-06$402M2025-09$194M2025-12−$2.7M2026-03$203M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on RYTM

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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