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Exagen (XGN) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 10, 2026

Exagen (XGN) reported revenue of $16.6M for the fourth quarter 2025 (Q4 2025), +22% from a year earlier and -4% from the quarter before. Operating margin was -29.9%, net loss $4.7M (28.1% of revenue).

Revenue$16.6M
Year over year+22%
Quarter over quarter-4%
Operating margin-29.9%
Net earnings−$4.7M

Exagen, Q4 2025: revenue $16.6M (+22% year over year), operating margin -29.9%, net loss $4.7M, operating cash flow −$3.0M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$16.6M-4%+22%
Operating profit−$5.0M——
Net earnings−$4.7M——
Operating cash flow−$3.0M-202%-930%

What changed

Revenue was $16.6M in Q4 2025, up 22% year over year and down 4% from the previous quarter.

Gross margin was 55.4%, down 6.7 points from Q4 2024. Operating costs exceeded revenue by $5.0M, an operating margin of -29.9%. Operating expenses grew 20% against revenue growth of 22%. The fastest-growing cost line was SG&A (+22%). The quarter ended with a net loss of $4.7M, narrower than the previous quarter's $7.1M loss.

Operating cash flow was −$3.0M. Non-cash charges added back $600K of depreciation and amortization and $705K of share-based compensation. Working capital and other items added $355K. Capital expenditures of $44K exceeded it, leaving free cash flow of −$3.1M.

Questions

What was Exagen's revenue in the fourth quarter 2025?

Exagen (XGN) reported revenue of $16.6M for the fourth quarter 2025 (Q4 2025), +22% from a year earlier and -4% from the quarter before.

Was Exagen profitable in the fourth quarter 2025?

Operating loss was $5.0M (-29.9% of revenue) and net loss $4.7M.

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Source: Exagen 10-K on SEC EDGAR.