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Xencor (XNCR) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 4, 2026 · Xencor (XNCR) Q3 2026 earnings results →

Q3 2026 Revenue up 455% year over year to $117M · 34¢ of every $1 of revenue kept as net profit · operating margin 19.6%

Xencor made $117M in Q3 2026 (+455% Y/Y): Royalties $87.5M, Milestone $29.0M. Operating margin 19.6%, net earnings $39.4M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 4, 2026.

Revenue$117M
Year over year+455%
Operating margin19.6%
Net earnings$39.4M
Operating cash flow$2.6M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $116.5M in Q3 2026, up 455% year over year and up 127% from the previous quarter. Royalties was the largest line at 75% of revenue. Royalties added $66.5M year over year (up 317%), 70% of the total change.

Operating profit was $22.9M, a 19.6% margin (up 245.9 points year over year). Total costs grew 37% against revenue growth of 455%. The fastest-growing cost line was Research & development (+55%). Net earnings were $39.4M. The effective tax rate was -0.4%. Non-operating items added $16.4M, 42% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $2.6M, 7% of net earnings. Non-cash charges added back $2.2M of depreciation and amortization and $9.4M of share-based compensation. Working capital and other items used $48.5M. Capital expenditures of $1.8M left free cash flow of $838K.

Quarterly history

Xencor revenue by quarterXencor revenue by quarter$32.7MQ1 2025$43.6MQ2 2025$21.0MQ3 2025$28.2MQ4 2025$4.5MQ1 2026$51.2MQ2 2026$117MQ3 2026
Xencor net earnings by quarterXencor net earnings by quarter−$48.6MQ1 2025−$30.8MQ2 2025−$6.0MQ3 2025−$6.7MQ4 2025−$129MQ1 2026−$21.7MQ2 2026$39.4MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 4, 2026$117M+455%19.6%$39.4M$2.6M
Q2 202610-QAug 5, 2026$51.2M+18%-72.4%−$21.7M−$55.7M
Q1 202610-QMay 6, 2026$4.5M-86%n/m−$129M−$67.6M
Q4 202510-KFeb 25, 2026$28.2M-46%-189.9%−$6.7M−$51.7M
Q3 202510-QNov 5, 2025$21.0M+18%-226.3%−$6.0M−$30.8M
Q2 202510-QAug 6, 2025$43.6M+82%-76.1%−$30.8M−$36.4M
Q1 202510-QMay 7, 2025$32.7M+105%-131.9%−$48.6M−$16.2M

Charts

Xencor: revenue growth, year over year and quarter over quarterXencor: revenue growth, year over year and quarter over quarterY/YQ/Q+105%Q1 2025+82%+33%Q2 2025+18%-52%Q3 2025-46%+34%Q4 2025-86%-84%Q1 2026+18%+400%Q2 2026+400%+127%Q3 2026
Latest (Q3 2026): Y/Y +400%, Q/Q +127%.
Xencor: where the cash came from (+) and went (−), TTM to Q3 2026Xencor: where the cash came from (+) and went (−), TTM to Q3 2026Other investing$194MOperating cash flow−$172MCash drawn (+) / kept (−)−$36.2MShares issued$16.7MCapital spending−$4.1MOther financing$1.6M
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Xencor: profit against cash, quarter by quarterXencor: profit against cash, quarter by quarterNet incomeOperating cash flow−$46.2M−$49.8MQ4 2024−$48.6M−$16.2MQ1 2025−$30.8M−$36.4MQ2 2025−$6.0M−$30.8MQ3 2025−$6.7M−$51.7MQ4 2025−$129M−$67.6MQ1 2026−$21.7M−$55.7MQ2 2026$39.4M$2.6MQ3 2026
Latest (Q3 2026): Net income $39.4M, Operating cash flow $2.6M.
Xencor: diluted shares by fiscal yearXencor: diluted shares by fiscal year57MFY202060MFY202160MFY202261MFY202365MFY202474MFY2025
+29.8% since FY2020: more shares outstanding (issuance, stock pay).
Xencor in its industry: growth against margin (225 companies, SIC 2834)Xencor in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMTVRDLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMXNCR (+300%, 20%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Xencor

We are a clinical-stage biopharmaceutical company focused on discovering and developing engineered antibody therapeutics to treat patients with cancer and autoimmune diseases, who have unmet medical needs. We use our protein engineering capabilities to design new technologies and XmAb ® drug candidates with improved properties and multi-target mechanisms of action. We advance these candidates into clinical-stage development, where we are conducting Phase 1 and Phase 2 studies for a broad portfolio of programs, to determine which programs to advance into later stages of development and potentially commercialization, which programs we partner to optimize development, and which programs we discontinue.

In its own words, from its 10-K, filed Feb 25, 2026.

Xencor against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +455% against the peers' median +10%. Operating margin: 19.6% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
XNCR XencorQ3 2026$117M+455%19.6%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Xencor 10-Q on SEC EDGAR · CIK 1326732 · Pharmaceutical Preparations

Guidance and outlook

Xencor: what its forward-looking statements are about (10-Q filed 2026-11-04)Xencor: what its forward-looking statements are about (10-Q filed 2026-11-04)Other9Legal & regulation3Demand3Costs2Products1The economy1
19 statements; tone +0.16 (−1 all cautious, +1 all confident); 5 hedged.
Xencor: outlook statements against the filing beforeXencor: outlook statements against the filing beforeConfident4Cautious1

13F: who owns XNCR and who is buying

Largest holders of XNCR (13F)Largest holders of XNCR (13F)BlackRock$220MPrimecap Management$164MBVF$115MVanguard Group$110MRTW Investments, LP$109MRA Capital Management, L.P.$84.9MState Street$79.8MVanguard Capital Management LLC$52.8MTCG Crossover Management, LLC$39.5MPrice T Rowe Associates$37.9M
Funds' net buying of XNCR by quarter (13F)Funds' net buying of XNCR by quarter (13F)$70.6M2024-09$73.6M2024-12$36.9M2025-03$36.2M2025-06−$16.5M2025-09−$8.7M2025-12$39.0M2026-03−$4.4M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on XNCR

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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