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Collegium Pharmaceutical vs Amphastar Pharmaceuticals: COLL and AMPH compared
Collegium Pharmaceutical is the larger company: $216M of revenue in its latest quarter (Q3 2026) against $208M for Amphastar Pharmaceuticals (Q3 2026). Amphastar Pharmaceuticals is growing faster (+8% against +3% a year earlier). Amphastar Pharmaceuticals is more profitable, with an operating margin of 24.5% against 13.3%.
Where the money goes: COLL and AMPH
Collegium Pharmaceutical (COLL) · Q3 2026
Collegium Pharmaceutical, Q3 2026: revenue $216M (+3% year over year), operating margin 13.3%, net earnings $21.8M, operating cash flow $86.5M. The chart follows the revenue to costs, profit and cash.
Amphastar Pharmaceuticals (AMPH) · Q3 2026
Amphastar Pharmaceuticals, Q3 2026: revenue $208M (+8% year over year), operating margin 24.5%, net earnings $37.8M, operating cash flow $43.3M. The chart follows the revenue to costs, profit and cash.
| Collegium Pharmaceutical (COLL) | Amphastar Pharmaceuticals (AMPH) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $216M | $208M |
| Revenue growth, Y/Y | +3% | +8% |
| Gross margin | 58.0% | 48.0% |
| Operating margin | 13.3% | 24.5% |
| Net earnings | $21.8M | $37.8M |
| Net margin | 10.1% | 18.2% |
| Operating cash flow | $86.5M | $43.3M |
| Free cash flow | $86.3M | $33.4M |
| Market value | $717M | $1.2B |
| P/E | 15.0× | 15.0× |
| Analysts’ mean target | $49.00 | $22.50 |
Where the revenue comes from
Collegium Pharmaceutical
- Belbuca: $57.7M (27%)
- Jornay PM: $51.9M (24%)
- Xtampza ER: $45.8M (21%)
- Azstarys: $26.5M (12%)
Questions
Which is bigger, Collegium Pharmaceutical or Amphastar Pharmaceuticals?
Collegium Pharmaceutical is the larger company: $216M of revenue in its latest quarter (Q3 2026) against $208M for Amphastar Pharmaceuticals (Q3 2026).
Is Collegium Pharmaceutical or Amphastar Pharmaceuticals growing faster?
Amphastar Pharmaceuticals is growing faster (+8% against +3% a year earlier).
Which is more profitable, Collegium Pharmaceutical or Amphastar Pharmaceuticals?
Amphastar Pharmaceuticals is more profitable, with an operating margin of 24.5% against 13.3%.
More: Collegium Pharmaceutical earnings · how Collegium Pharmaceutical makes money · Amphastar Pharmaceuticals earnings · how Amphastar Pharmaceuticals makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 5, 2026; 10-Q filed Nov 5, 2026). Fiscal quarters can end on different dates. Not investment advice.