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Spero Therapeutics vs Oncotelic Therapeutics: SPRO and OTLC compared

Spero Therapeutics is the larger company: $258K of revenue in its latest quarter (Q1 2026) against $250K for Oncotelic Therapeutics (Q2 2026).

Spero Therapeutics vs Oncotelic Therapeutics, latest quarterSpero Therapeutics vs Oncotelic Therapeutics, latest quarterSpero Therapeutics (SPRO)Oncotelic Therapeutics (OTLC)Revenue$258K$250KOperating marginn/m-337.4%

Where the money goes: SPRO and OTLC

Spero Therapeutics (SPRO) · Q1 2026

Spero Therapeutics, Q1 2026: revenue $258K (-96% year over year), net loss $7.2M, operating cash flow $15.9M. The chart follows the revenue to costs, profit and cash.

Oncotelic Therapeutics (OTLC) · Q2 2026

Oncotelic Therapeutics, Q2 2026: revenue $250K, operating margin -337.4%, net earnings $341K, operating cash flow −$92K. The chart follows the revenue to costs, profit and cash.

Spero Therapeutics (SPRO)Oncotelic Therapeutics (OTLC)
Latest quarterQ1 2026Q2 2026
Revenue$258K$250K
Revenue growth, Y/Y-96%—
Operating marginn/m-337.4%
Net earnings−$7.2M$341K
Net margin—136.4%
Operating cash flow$15.9M−$92K

Questions

Which is bigger, Spero Therapeutics or Oncotelic Therapeutics?

Spero Therapeutics is the larger company: $258K of revenue in its latest quarter (Q1 2026) against $250K for Oncotelic Therapeutics (Q2 2026).

More: Spero Therapeutics earnings · how Spero Therapeutics makes money · Oncotelic Therapeutics earnings · how Oncotelic Therapeutics makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed May 13, 2026; 10-Q filed Aug 13, 2026). Fiscal quarters can end on different dates. Not investment advice.