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TG Therapeutics vs Ionis Pharmaceuticals: TGTX and IONS compared
TG Therapeutics is the larger company: $260M of revenue in its latest quarter (Q3 2026) against $243M for Ionis Pharmaceuticals (Q3 2026). TG Therapeutics is growing faster (+61% against +55% a year earlier). TG Therapeutics is more profitable, with an operating margin of 33.0% against -53.8%.
Where the money goes: TGTX and IONS
TG Therapeutics (TGTX) · Q3 2026
TG Therapeutics, Q3 2026: revenue $260M (+61% year over year), operating margin 33.0%, net earnings $55.5M. The chart follows the revenue to costs, profit and cash.
Ionis Pharmaceuticals (IONS) · Q3 2026
Ionis Pharmaceuticals, Q3 2026: revenue $243M (+55% year over year), operating margin -53.8%, net loss $110M, operating cash flow −$179M. The chart follows the revenue to costs, profit and cash.
| TG Therapeutics (TGTX) | Ionis Pharmaceuticals (IONS) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $260M | $243M |
| Revenue growth, Y/Y | +61% | +55% |
| Operating margin | 33.0% | -53.8% |
| Net earnings | $55.5M | −$110M |
| Net margin | 21.3% | -45.3% |
| Operating cash flow | — | −$179M |
| Market value | $8.7B | $7.1B |
| P/E | 19.7× | — |
| Analysts’ mean target | $69.71 | $84.13 |
Where the revenue comes from
TG Therapeutics
- Product revenue, net: $240M (92%)
- License, milestone, royalty and other revenue: $19.9M (8%)
Ionis Pharmaceuticals
- Commercial Revenue: $136M (56%)
- Research and Development Revenue: $107M (44%)
Questions
Which is bigger, TG Therapeutics or Ionis Pharmaceuticals?
TG Therapeutics is the larger company: $260M of revenue in its latest quarter (Q3 2026) against $243M for Ionis Pharmaceuticals (Q3 2026).
Is TG Therapeutics or Ionis Pharmaceuticals growing faster?
TG Therapeutics is growing faster (+61% against +55% a year earlier).
Which is more profitable, TG Therapeutics or Ionis Pharmaceuticals?
TG Therapeutics is more profitable, with an operating margin of 33.0% against -53.8%.
More: TG Therapeutics earnings · how TG Therapeutics makes money · Ionis Pharmaceuticals earnings · how Ionis Pharmaceuticals makes money
From the companies' latest 10-Q, 10-K or earnings release (8-K filed Nov 9, 2026; 10-Q filed Nov 9, 2026). Fiscal quarters can end on different dates. Not investment advice.