Filing Flows › Personalis (PSNL) › Q3 2025
Personalis (PSNL) Q3 2025 earnings results (third quarter 2025)
10-Q filed Nov 4, 2025
Personalis (PSNL) reported revenue of $14.5M for the third quarter 2025 (Q3 2025), -44% from a year earlier and -16% from the quarter before. Operating margin was -160.7%, net loss $21.7M (149.4% of revenue).
Personalis, Q3 2025: revenue $14.5M (-44% year over year), operating margin -160.7%, net loss $21.7M, operating cash flow −$21.8M. The chart follows the revenue to costs, profit and cash.
| Q3 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $14.5M | -16% | -44% |
| Operating profit | −$23.3M | — | — |
| Net earnings | −$21.7M | — | — |
| Operating cash flow | −$21.8M | — | — |
What changed
Revenue was $14.5M in Q3 2025, down 44% year over year and down 16% from the previous quarter.
Operating costs exceeded revenue by $23.3M, an operating margin of -160.7%. Total costs fell 6% while revenue fell 44%. The fastest-growing cost line was SG&A (+14%). The quarter ended with a net loss of $21.7M, wider than the previous quarter's $20.1M loss.
Operating cash flow was −$21.8M. Non-cash charges added back $2.5M of depreciation and amortization and $2.1M of share-based compensation. Working capital and other items used $4.7M. Capital expenditures of $1.6M exceeded it, leaving free cash flow of −$23.4M.
Questions
What was Personalis' revenue in the third quarter 2025?
Personalis (PSNL) reported revenue of $14.5M for the third quarter 2025 (Q3 2025), -44% from a year earlier and -16% from the quarter before.
Was Personalis profitable in the third quarter 2025?
Operating loss was $23.3M (-160.7% of revenue) and net loss $21.7M.
Source: Personalis 10-Q on SEC EDGAR.