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aTYR Pharma (ATYR) earnings and revenue breakdown

Latest: Q3 2025 · 10-Q filed Nov 6, 2025 · aTYR Pharma (ATYR) Q3 2025 earnings results →

aTYR Pharma made $190K in Q3 2025. Operating margin n/m, net loss $25.7M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 6, 2025.

Revenue$190K
Year over year—
Operating marginn/m
Net earnings−$25.7M
Operating cash flow−$20.5M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $190K in Q3 2025.

Operating costs exceeded revenue by $26.7M, an operating margin of -14076.3%. The quarter ended with a net loss of $25.7M. Minority interests bore $2K of it: to shareholders the quarter was a loss of $25.7M.

Operating cash flow was −$20.5M. Non-cash charges added back $165K of depreciation and amortization and $1.3M of share-based compensation. Working capital and other items added $3.8M. Capital expenditures of $37K exceeded it, leaving free cash flow of −$20.5M.

Quarterly history

QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202510-QNov 6, 2025$190K—n/m−$25.7M−$20.5M

Charts

aTYR Pharma: where the cash came from (+) and went (−), TTM to Q3 2026aTYR Pharma: where the cash came from (+) and went (−), TTM to Q3 2026Other investing$49.3MOperating cash flow−$43.6MCash drawn (+) / kept (−)−$5.8MOther financing$911KNet borrowing (+) / repaid (−)−$540KCapital spending−$287K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
aTYR Pharma: profit against cash, quarter by quarteraTYR Pharma: profit against cash, quarter by quarterNet incomeOperating cash flow−$15.0M−$13.1MQ4 2024−$14.9M−$15.4MQ1 2025−$19.5M−$13.9MQ2 2025−$25.7M−$20.5MQ3 2025−$14.0M−$12.2MQ4 2025−$10.8M−$12.5MQ1 2026−$10.3M−$9.4MQ2 2026−$18.3M−$9.5MQ3 2026
Latest (Q3 2026): Net income −$18.3M, Operating cash flow −$9.5M.
aTYR Pharma: diluted shares by fiscal year (split-adjusted)aTYR Pharma: diluted shares by fiscal year (split-adjusted)37MFY202038MFY202157MFY202254MFY202374MFY202493MFY2025
+153.8% since FY2020: more shares outstanding (issuance, stock pay); earlier years scaled for the 2-for-1 split before FY2023, 2-for-1 split before FY2021.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About aTYR Pharma

aTyr is a clinical stage biotechnology company leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. tRNA synthetases are ancient, essential proteins that have evolved novel domains that regulate diverse pathways extracellularly in humans. aTyr’s discovery platform is focused on unlocking hidden therapeutic intervention points by uncovering signaling pathways driven by its proprietary library of domains derived from all 20 tRNA synthetases. aTyr’s lead therapeutic candidate is efzofitimod, a novel biologic immunomodulator in clinical development for the treatment of interstitial lung disease, a group of immune-mediated disorders that can cause inflammation and progressive fibrosis, or scarring, of the lungs. For more information, please visit www.atyrpharma.com .

In its own words, from its 8-K, filed Aug 7, 2026.

aTYR Pharma against its Biological Products, (No Diagnostic Substances) peers

The largest companies of the same SEC industry, each at its latest quarter.

CompanyQuarterRevenueY/YOp. margin
ATYR aTYR PharmaQ3 2025$190K—n/m
AMGN AmgenQ3 2026$10.4B+8%35.8%
GILD Gilead SciencesQ3 2026$8.3B+7%41.7%
BIIB BiogenQ3 2026$2.8B+11%-0.3%
MRNA ModernaQ3 2026$1.3B+29%9.9%
NBIX Neurocrine BiosciencesQ3 2026$1.1B+41%29.5%
EXEL ExelixisQ3 2026$659M+10%40.8%
HALO Halozyme TherapeuticsQ3 2026$493M+39%59.8%
MGTX MeiraGTx HoldingsQ2 2026$321M87×76.0%

Source: aTYR Pharma 10-Q on SEC EDGAR · CIK 1339970 · Biological Products, (No Diagnostic Substances)

13F: who owns ATYR and who is buying

Largest holders of ATYR (13F)Largest holders of ATYR (13F)Federated Hermes$5.1MVanguard Group$3.9MVanguard Capital Management LLC$2.3MKalehua Capital Management LLC$2.1MGSA Capital Partners LLP$2.1MAQR Capital Management LLC$1.6MFMR LLC$1.5MBlackRock$1.1MJane Street Group, LLC$1.0MUBS Group AG$914K
Funds' net buying of ATYR by quarter (13F)Funds' net buying of ATYR by quarter (13F)−$6.2M2024-09$32.3M2024-12$20.1M2025-03$23.7M2025-06−$3.4M2025-09−$5.2M2025-12$799K2026-03−$9.2M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on ATYR

History

Every quarter: Q3 2025 results

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