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Caribou Biosciences (CRBU) earnings and revenue breakdown

Latest: Q3 2026 · 10-Q filed Nov 5, 2026 · Caribou Biosciences (CRBU) Q3 2026 earnings results →

Q3 2026 Revenue down 27% year over year to $1.6M

Caribou Biosciences made $1.6M in Q3 2026 (-27% Y/Y). Operating margin n/m, net loss $26.6M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed Nov 5, 2026.

Revenue$1.6M
Year over year-27%
Operating marginn/m
Net earnings−$26.6M
Operating cash flow−$22.5M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $1.6M in Q3 2026, down 27% year over year and up 7% from the previous quarter.

Operating costs exceeded revenue by $27.6M, an operating margin of -1720.1%. Total costs fell 7% while revenue fell 27%. The quarter ended with a net loss of $26.6M, wider than the previous quarter's $24.3M loss.

Operating cash flow was −$22.5M. Non-cash charges added back $590K of depreciation and amortization and $2.2M of share-based compensation. Working capital and other items added $1.3M. Capital expenditures of $19K exceeded it, leaving free cash flow of −$22.5M.

Quarterly history

Caribou Biosciences revenue by quarterCaribou Biosciences revenue by quarter$2.4MQ1 2025$2.7MQ2 2025$2.2MQ3 2025$3.9MQ4 2025$2.4MQ1 2026$1.5MQ2 2026$1.6MQ3 2026
Caribou Biosciences net earnings by quarterCaribou Biosciences net earnings by quarter−$40.0MQ1 2025−$54.1MQ2 2025−$27.5MQ3 2025−$26.5MQ4 2025−$25.1MQ1 2026−$24.3MQ2 2026−$26.6MQ3 2026
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q3 202610-QNov 5, 2026$1.6M-27%n/m−$26.6M−$22.5M
Q2 202610-QAug 13, 2026$1.5M-44%n/m−$24.3M−$22.8M
Q1 202610-QMay 7, 2026$2.4M+2%n/m−$25.1M−$27.0M
Q4 202510-KMar 5, 2026$3.9M+90%-722.0%−$26.5M−$20.8M
Q3 202510-QNov 12, 2025$2.2M+9%n/m−$27.5M−$25.2M
Q2 202510-QAug 12, 2025$2.7M-23%n/m−$54.1M−$28.3M
Q1 202510-QMay 8, 2025$2.4M-3%n/m−$40.0M−$36.7M

Charts

Caribou Biosciences: revenue growth, year over year and quarter over quarterCaribou Biosciences: revenue growth, year over year and quarter over quarterY/YQ/Q-3%Q1 2025-23%+13%Q2 2025+9%-18%Q3 2025+90%+79%Q4 2025+2%-39%Q1 2026-44%-37%Q2 2026-27%+7%Q3 2026
Latest (Q3 2026): Y/Y -27%, Q/Q +7%.
Caribou Biosciences: where the cash came from (+) and went (−), TTM to Q3 2026Caribou Biosciences: where the cash came from (+) and went (−), TTM to Q3 2026Operating cash flow−$93.1MOther investing$79.8MShares issued$27.7MCash drawn (+) / kept (−)−$14.9MAsset & business sales$317KCapital spending$124KOther financing$31K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Caribou Biosciences: profit against cash, quarter by quarterCaribou Biosciences: profit against cash, quarter by quarterNet incomeOperating cash flow−$35.5M−$35.5MQ4 2024−$40.0M−$36.7MQ1 2025−$54.1M−$28.3MQ2 2025−$27.5M−$25.2MQ3 2025−$26.5M−$20.8MQ4 2025−$25.1M−$27.0MQ1 2026−$24.3M−$22.8MQ2 2026−$26.6M−$22.5MQ3 2026
Latest (Q3 2026): Net income −$26.6M, Operating cash flow −$22.5M.
Caribou Biosciences: diluted shares by fiscal year (split-adjusted)Caribou Biosciences: diluted shares by fiscal year (split-adjusted)68MFY202063MFY202161MFY202274MFY202390MFY202493MFY2025
+36.6% since FY2020: more shares outstanding (issuance, stock pay); earlier years scaled for the 2-for-1 split before FY2022, 4-for-1 split before FY2021.
Caribou Biosciences in its industry: growth against margin (76 companies, SIC 2836)Caribou Biosciences in its industry: growth against margin (76 companies, SIC 2836)revenue growth, year over year →↑ operating marginmedian +9%median -100%AMGNGILDBIIBMRNANBIXEXELHALOMGTXTECHVIRRGENTARSBCRXALECADMAKRYSIOVATWSTIPSCIMCRVISKVCELADPTNVAXKYMRGLUEIBRXAUTLAGENDNAPLXRXRXFENCCSBRCHRSIVVDCRSPEDITDTILVXRTSTRORGNXCCCCBSEMSCLXACOGTSHASRZNVYGRFDMTLENZALGSXFORELUTFATEOCGNSCTXCGONDBVTINBXMGXLCTXTCRXDYAIPRMEATRAVitro Biopharma, Inc.HUMARLAYPLURBEAMPROKCRDFAIMVIVSCRBU (-27%, -100%)
Biological Products, (No Diagnostic Substances); dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Caribou Biosciences

We are a clinical-stage C lustered R egularly I nterspaced S hort P alindromic R epeats (“CRISPR”) genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. Our genome-editing platform is based on our novel chRDNA ( C RISPR h ybrid R NA- DNA , or “chRDNA,” pronounced “chardonnay”) genome-editing technology, which enables more precise genome editing of allogeneic cell therapies. Our allogeneic, or off-the-shelf, chimeric antigen receptor (“CAR”) -T (“CAR-T”) cell therapy product candidates are manufactured in advance with cells from healthy donors, with the goal of enabling broad patient access, rapid patient treatment, and increased manufacturing scale.

In its own words, from its 10-K, filed Mar 5, 2026.

Caribou Biosciences against its Biological Products, (No Diagnostic Substances) peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: -27% against the peers' median +11%.

CompanyQuarterRevenueY/YOp. margin
CRBU Caribou BiosciencesQ3 2026$1.6M-27%n/m
AMGN AmgenQ3 2026$10.4B+8%35.8%
GILD Gilead SciencesQ3 2026$8.3B+7%41.7%
BIIB BiogenQ3 2026$2.8B+11%-0.3%
MRNA ModernaQ3 2026$1.3B+29%9.9%
NBIX Neurocrine BiosciencesQ3 2026$1.1B+41%29.5%
EXEL ExelixisQ3 2026$659M+10%40.8%
HALO Halozyme TherapeuticsQ3 2026$493M+39%59.8%
MGTX MeiraGTx HoldingsQ2 2026$321M87×76.0%

Source: Caribou Biosciences 10-Q on SEC EDGAR · CIK 1619856 · Biological Products, (No Diagnostic Substances)

Guidance and outlook

Caribou Biosciences: what its forward-looking statements are about (10-Q filed 2026-11-05)Caribou Biosciences: what its forward-looking statements are about (10-Q filed 2026-11-05)Demand2Costs2Legal & regulation1Other1Financing1
7 statements; tone +0.00 (−1 all cautious, +1 all confident); 0 hedged.

13F: who owns CRBU and who is buying

Largest holders of CRBU (13F)Largest holders of CRBU (13F)BlackRock$13.8MPfizer$7.9MVanguard Capital Management LLC$7.4MVanguard Group$6.8MMackenzie Financial$5.2MRenaissance Technologies LLC$4.9MKynam Capital Management, LP$4.4MGeode Capital Management, LLC$4.2MAcadian Asset Management LLC$3.1MState Street$2.9M
Funds' net buying of CRBU by quarter (13F)Funds' net buying of CRBU by quarter (13F)$2.5M2024-09$1.7M2024-12−$4.4M2025-03−$9.5M2025-06−$9.7M2025-09$3K2025-12$1.4M2026-03$18.9M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on CRBU

History

Every quarter: Q3 2026 results · Q2 2026 results · Q1 2026 results · Q4 2025 results · Q3 2025 results · Q2 2025 results · Q1 2025 results

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